McGhan

January 22, 1993

Feargal Judge

General Manager

McGhan Limited

Kilbride Industrial Estates

Arklow County Wicklow

Ireland

Dear Feargal,

Enclosed are two reports. The first report is from Valerie Mandrell, revising the package inserts. She has made several changes providing consistency with current McGhan Medical packaging. It is felt that these changes can be incorporated upon the next purchase of inserts and that these changes should not delay market release.

The second report is the Technical Report on the Style 177 physical characteristics. In summary, all product passed testing, but just hardly in some instances. The outer lumen shells are on the low end of the specification, therefore, leading to reduced physical characteristics. It is suggested that the outer lumen shell thickness be increased within the present ranges in your future runs.

We wish you a great success with this product and I hope to meet you in the homeland” in the near future.

Sincerely,

Patrick O’Leary,  Ph.D.

Manager, Technologies

PO:ar

cc:    J. McGhan
J. Barber